Proton beam radiotherapy: report of the first patient treated at the Centro Nazionale di Adroterapia Oncologica (CNAO).

TitleProton beam radiotherapy: report of the first patient treated at the Centro Nazionale di Adroterapia Oncologica (CNAO).
Publication TypeJournal Article
Year of Publication2013
AuthorsOrecchia R, Srivastava A, Fiore MRosaria, Vitolo V, Fossati P, Vischioni B, Iannalfi A, Tuan J, Ciocca M, Molinelli S, Mirandola A, Vilches G, Mairani A, Tagaste B, Baroni G, Rossi S, Krengli M
JournalTumori
Volume99
Issue2
Pagination34e-7e
Date Published2013 Mar-Apr
ISSN2038-2529
Abstract

Proton beam radiotherapy, an innovative treatment modality, allows delivery of high radiation doses to the target while sparing surrounding healthy structures. The Centro Nazionale di Adroterapia Oncologica (CNAO), equipped with a synchrotron and capable of using both protons and ions, initiated its clinical activity in September 2011. The first treatment of a skull base tumor with protons is reported here. The case of a 26-year-old man with an intracranial low-grade chondrosarcoma of the right petroclival junction is discussed with emphasis on technical and clinical details. Two previous surgical interventions had achieved partial removal of the tumor and the patient was treated with protons for residual disease. The prescribed dose was 70 GyE in 35 fractions of 2 GyE. Treatment was completed with minimal acute toxicity consisting of grade 1 alopecia and nausea. Nine months after treatment the disease is locally controlled. Use of high-energy protons at CNAO is a safe and effective means of treating a tumor located near critical normal structures.

DOI10.1700/1283.14204
Alternate JournalTumori
PubMed ID23748826

You are here